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SECRET OF LONGEVITY REVEALED?

Being healthier for longer as you age is the key to amore fulfilling life. Now, anew study has identified a communication pathway connecting the brain and body in afeedback loop that appears central to energy production. The gradual deterioration ofthis feedback loop contributes to increasing health problems typical ofnatural ageing. But researchers from Washington University School of Medicine studied mice that were programmed to have this communication pathway constantly open. These mice were more physically active, showed signs ofdelayed ageing, looked younger and lived longer than mice with a naturally slowing communication pathway. This discovery opens the possibility of developing interventions tomaintain the feedback loop longer and slow the effects of ageing.

Scratching that itch

As people with eczema, allergies or autoimmune conditions know all too well, when an itch gets out of control, it becomes a serious health problem. Now, scientists at UC San Francisco have discovered a feedback loop from a single immune protein that both causes the urge to itch and dials back nearby inflammation. The team found that nerve cells which respond to the protein, triggering an itch, also prevent immune cells from overreac ting and causing more widespread irritation. This could lay the groundwork for a new generation of drugs that interact more intelligently with your body's ability to self-regulate – dampening down that itchy feeling.

TOP OF THE PODS

Kickstart your spring cleaning with the motivational podcast ClutterBug (clut terbug.com). It helps you organise, declutter and take back control of your home! Find all the tips, tricks and shor tcuts to make cleaning and clearing out your living space a happier and easier experience. Recent episodes include creating new habits, cleaning wisdom, tough-love advice and undiagnosed ADHD in women.

NEW LIFE-SAVER

Antibiotic-resistant bacteria are a major threat to public health, with 58,224 people in England having an antibioticresistant infection in 2022 – a rise of 4 per cent from the previous year . Without new antibiotics, even common injuries and infections have the potential to be lethal. Now, scientists from Texas A&M University have created a new substance capable of killing bacteria, which is a big breakthrough in the fight against superbugs like E. coli and MRSA. It’s set to be an important step for ward for saving lives.

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